KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN2
All Species:
34.24
Human Site:
Y676
Identified Species:
57.95
UniProt:
Q16513
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16513
NP_006247.1
984
112035
Y676
G
K
V
L
L
A
E
Y
K
N
T
N
E
M
F
Chimpanzee
Pan troglodytes
XP_001145367
984
112028
Y676
G
K
V
L
L
A
E
Y
K
H
T
N
E
M
F
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
E707
I
K
A
L
K
K
Q
E
V
L
S
R
D
E
I
Dog
Lupus familis
XP_547295
1021
115999
Y713
G
K
V
L
L
A
E
Y
K
H
T
N
E
M
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWW9
983
111611
Y675
G
K
V
L
L
A
E
Y
K
H
T
N
E
M
F
Rat
Rattus norvegicus
O08874
985
112050
Y677
G
K
V
L
L
A
E
Y
K
H
T
N
E
M
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
Y689
A
K
G
T
G
R
H
Y
A
I
K
A
L
K
K
Chicken
Gallus gallus
XP_422357
1013
114806
Y705
G
K
V
L
L
A
E
Y
K
N
T
N
E
M
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700704
970
110327
Y662
G
K
V
L
L
A
E
Y
T
I
T
G
E
M
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
D343
K
D
A
I
I
Q
D
D
D
V
D
C
T
M
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
Q416
L
K
K
D
V
I
V
Q
D
D
D
V
E
C
T
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
V508
K
A
L
K
K
R
D
V
V
A
R
E
E
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
S843
G
K
V
I
L
S
K
S
K
N
T
D
R
L
C
Red Bread Mold
Neurospora crassa
P87253
1142
127954
T836
G
K
V
M
L
A
E
T
K
K
S
R
K
L
Y
Conservation
Percent
Protein Identity:
100
99.6
46.1
92.8
N.A.
94.6
92.6
N.A.
53.9
87
N.A.
76.4
N.A.
28.3
N.A.
27.6
48.4
Protein Similarity:
100
99.9
63.2
94.7
N.A.
97.2
95.3
N.A.
68.2
91.9
N.A.
85
N.A.
42.3
N.A.
43.7
61.3
P-Site Identity:
100
93.3
13.3
93.3
N.A.
93.3
93.3
N.A.
13.3
100
N.A.
80
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
13.3
100
N.A.
80
N.A.
26.6
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
27.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
45.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
0
0
58
0
0
8
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% C
% Asp:
0
8
0
8
0
0
15
8
15
8
15
8
8
0
0
% D
% Glu:
0
0
0
0
0
0
58
8
0
0
0
8
65
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% F
% Gly:
65
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
29
0
0
0
0
0
% H
% Ile:
8
0
0
15
8
8
0
0
0
15
0
0
0
0
8
% I
% Lys:
15
86
8
8
15
8
8
0
58
8
8
0
8
8
8
% K
% Leu:
8
0
8
58
65
0
0
0
0
8
0
0
8
15
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
58
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
22
0
43
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
15
0
0
0
0
8
15
8
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
0
0
15
0
0
0
0
% S
% Thr:
0
0
0
8
0
0
0
8
8
0
58
0
8
0
15
% T
% Val:
0
0
65
0
8
0
8
8
15
8
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _